Browsing by Author "Cevik, Betul"
Now showing items 1-20 of 27
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Analysis of MMP2-1306C/T and TIMP2G-418C polymorphisms with relapsing remitting multiple sclerosis
Aksoy, Durdane; Ates, Omer; Kurt, Semiha; Cevik, Betul; Sumbul, Orhan (Bmj Publishing Group, 2016)Aims Multiple sclerosis (MS) is an autoimmune, inflammatory disease characterized by loss of myelin forming oligodendrocytes and changes in the blood-brain barrier. Matrix metalloproteinase (MMP) -2 and -9 are known to ... -
Association of interleukin (IL)-4 gene intron 3 VNTR polymorphism with multiple sclerosis in Turkish population
Karakus, Nevin; Yigit, Serbulent; Kurt, Gulsum Semiha; Cevik, Betul; Demir, Osman; Ates, Omer (Elsevier Science Inc, 2013)Objective: Genetic risk factors are known to contribute to the etiology of multiple sclerosis (MS). Interleukin (IL)-4 gene polymorphisms have been associated with immune-mediated diseases. The aim of this study was to ... -
Association of Methylenetetrahydrofolate Reductase Gene C677T Polymorphism With Multiple Sclerosis in Turkish Patients
Cevik, Betul; Yigit, Serbulent; Karakus, Nevin; Aksoy, Durdane; Kurt, Semiha; Ates, Omer (Bmj Publishing Group, 2014)Background and Aim: Multiple sclerosis (MS) is a chronic neurodegenerative autoimmune disease of the central nervous system. Genetic risk factors are known to contribute to the etiology of MS. Methylenetetrahydrofolate ... -
Atypical Features in a Large Turkish Family Affected with Friedreich Ataxia
Kurt, Semiha; Cevik, Betul; Aksoy, Durdane; Sahbaz, E. Irmak; Eken, Asli Gundogdu; Basak, A. Nazli (Hindawi Ltd, 2016)Here, we describe the clinical features of several members of the same family diagnosed with Friedreich ataxia ( FRDA) and cerebral lesions, demyelinating neuropathy, and late-age onset without a significant cardiac ... -
Central corneal thickness and its relationship to Parkinson's disease severity
Aksoy, Durdane; Ortak, Huseyin; Kurt, Semiha; Cevik, Emre; Cevik, Betul (Canadian Ophthal Soc, 2014)Objective: To investigate the effect of Parkinson's disease (PD) on blink rate (BR), tear breakup time test (TBUT). Schirmer's test, and corneal thickness, and the relationship of these effects with disease severity. Design: ... -
Characteristics of headache and its relationship with disease severity in patients with Crimean-Congo hemorrhagic fever
Aksoy, Durdane; Barut, Hatice; Duygu, Fazilet; Cevik, Betul; Kurt, Semiha; Sumbul, Orhan (Kare Publ, 2018)Objectives: Crimean-Congo Hemorrhagic Fever (CCHF) is a fatal, tick- borne disease. The classic clinical presentation of CCHF is characterized by sudden onset of high fever, chills, and severe headache. There are no previous ... -
Clinical, demographic and prognostic features of sporadic amyotrophic lateral sclerosis in Northern Turkey
Aksoy, Durdane; Cevik, Betul; Solmaz, Volkan; Kurt, Semiha Gulsum (Taylor & Francis Ltd, 2014)Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease for which progression cannot be prevented. In this study, we evaluated 37 patients diagnosed with sporadic definitive-probable ALS who were monitored in ... -
The Effect of Autologous Fat Graft with Different Surgical Repair Methods on Nerve Regeneration in a Rat Sciatic Nerve Defect Model
Tuncel, Umut; Kostakoglu, Naci; Turan, Aydin; Cevik, Betul; Cayli, Sevil; Demir, Osman; Elmas, Cigdem (Lippincott Williams & Wilkins, 2015)Background: The aim of this study was to evaluate the efficacy of autologous fat graft with different surgical repair methods on reconstruction of a 10-mm-long rat sciatic nerve defect model. Methods: One hundred forty-four ... -
An electrophysiologic evaluation of whether open and laparoscopic techniques used in pediatric inguinal hernia repairs affect the genitofemoral nerve
Celebi, Suleyman; Aksoy, Durdane; Cevik, Betul; Yildiz, Abdullah; Kurt, Semiha; Dokucu, Ali Ihsan (W B Saunders Co-Elsevier Inc, 2013)Background: A prospective study was performed to evaluate the effect of inguinal hernia repairs on the genitofemoral nerve (GFN), and to compare postoperative electrophysiologic changes in the GFN of patients who had ... -
ERLIN1 mutations cause teenage-onset slowly progressive ALS in a large Turkish pedigree
Tunca, Ceren; Akcimen, Fulya; Coskun, Cemre; Gundogdu-Eken, Asli; Kocoglu, Cemile; Cevik, Betul; Bekircan-Kurt, Can Ebru (Nature Publishing Group, 2018)Amyotrophic lateral sclerosis (ALS) is a late-onset motor neuron disease with mostly dominant inheritance and a life expectancy of 2-5 years; however, a quite common occurrence of atypical forms of the disease, due to ... -
Evaluation of different ulegyria patterns with magnetic resonance imaging
Gokce, Erkan; Cevik, Betul (Elsevier Sci Ltd, 2018)Ulegyria is a parenchymal sequel of hypoxic ischemic encephalopathy causing mushroom-like appearance in gyri. Aim of the present study was to evaluate clinico-radiological findings of patients who applied with different ... -
The evaluation of sexual dysfunction in male patients with migraine and tension type headache
Aksoy, Durdane; Solmaz, Volkan; Cevik, Betul; Gencten, Yusuf; Erdemir, Fikret; Kurt, Semiha Gulsum (Bmc, 2013)Background: Erectile dysfunction (ED), defined as the inability to achieve or maintain an erection sufficient for satisfactory sexual performance, is a common condition. The psychological, hormonal, neurogenic and arterial ... -
The Evaluation of the Ganglion Cell Layer-Inner Plexiform Layer Complex Thickness in Early Parkinson's Disease
Aksoy, Durdane; Demir, Selim; Ortak, Huseyin; Cevik, Betul; Sumbul, Orhan; Kurt, Semiha (Lippincott Williams & Wilkins, 2018) -
Frontal lobe syndrome developing after head trauma: case report
Cevik, Betul; Yildirim, Ali; Aksoy, Durdane; Ozer, Erdal; Kurt, Semiha (Cumhuriyet Univ Tip Fak Psikiyatri Anabilim Dali, 2015)Frontal lobe syndrome (FLS) is a clinical picture caused by damages due to reasons like prefrontal cortex cerebrovascular disease, tumor, infection or head trauma and displaying itself through distinct and permanent ... -
Hypokalemia and hypomagnesaemia related to levetiracetam use
Aksoy, Durdane; Cevik, Betul; Kurt, Semiha; Pekdas, Elmas; Solmaz, Volkan (Elsevier Sci Ltd, 2014)Levetiracetam (LEV), used for both partial and generalized seizures, is a frequently preferred antiepileptic because of its few side effects. We present a 23-year-old man who developed hypokalemia after switching from ... -
The Importance of Hypothermia in the Effects of Paracetamol on the Electrical Activity of the Brain in Pentylenetetrazole Induced Experimental Status Epilepticus in Rats
Kurt, Semiha; Aygun, Hatice; Ozsoy, Seyma; Cevik, Betul; Aksoy, Durdane; Sumbul, Orhan (Kare Publ, 2020)Objectives: Paracetamol is a commonly used analgesic and antipyretic agent. In studies investigating the effects of paracetamol on seizure activity, to our knowledge, the hypothermic effect has not been evaluated in studies ... -
The investigation of association between IL-1Ra and ACE I/D polymorphisms in carpal tunnel syndrome
Cevik, Betul; Tekcan, Akin; Inanir, Ahmet; Kurt, Semiha Gulsum; Yigit, Serbulent (Wiley, 2018)BackgroundCarpal tunnel syndrome (CTS) is a common neurologic impairment caused by injury on the median nerve in the wrist, characterized by pain and loss of sensory. CTS usually occurs through three factors, such as a ... -
Lack of Association Between MIF Gene-173G>C Polymorphism with Multiple Sclerosis
Cevik, Betul; Yigit, Serbulent; Karakus, Nevin; Aksoy, Durdane; Ates, Omer; Kurt, Semiha (Int Inst Anticancer Research, 2015)Aim: The aim of the present study was to investigate a possible association between the MIF -173G>C polymorphism and MS in Turkish patients. Materials and Methods: The study included 153 MS-patients and 210 controls. Genomic ...
