Browsing by Author "Budak, Yakup"
Now showing items 1-20 of 45
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1-Fenilsiklohekza-1,2-dien'in sentezi ve 1-(2,3-dibromosiklohekz-1-en-1-il) benzen'in metalik çinko ile reaksiyonu
Budak, Yakup (Gaziosmanpaşa Üniversitesi Fen Bilimleri Enstitüsü, 1999)[No Abstract Available] -
1-Fenilsiklohepta-1,2-Dien'in sentezi ve yakalanması üzerine çalışmalar
Budak, Yakup (Gaziosmanpaşa Üniversitesi Fen Bilimleri Enstitüsü, 2005)[No Abstract Available] -
4-Fenil-2-(Tiyofen-3-il)-6,7-Dihidro-5H siklopenta (b)piridin türevlerinin sentezi
Yılmaz, Burhan (2012)[No Abstract Available] -
4-Fenil-2-(Tiyofen-3-il)-6,7-Dihidro-5H-siklopenta[b] piridin türevlerinin sentezi
Yılmaz, Burhan (Gaziosmanpaşa Üniversitesi, Fen Bilimleri Enstitüsü, 2012)[No Abstract Available] -
Attempted synthesis of 1-cyclohepta-1,2-dien-1-ylbenzene and Wurtz-like condensation products in the reaction of 1-(2,3-dibromocyclohept-1-en-1-yl) benzene with zinc
Ceylan, Mustafa; Budak, Yakup; Gürdere, M. Burcu (2006)7,7-Dibromo-1-phenylbicyclo[4.1.0]heptane 4 was synthesized and its thermal and silver ion-catalyzed rearrangements were studied. Alcohol 8 was converted to 1-(2,3-dibromocyclohept-1-en-1-yl)benzene 6. The zinc-mediated ... -
Bromination of 1,4-diphenylbutane-1,4-dione with N-bromosuccinimide and bromine in different conditions
Guerdere, Meliha Burcu; Budak, Yakup; Gezegen, Hayrettin; Ceylan, Mustafa (Asian Journal Of Chemistry, 2008)The trans-1,2-dibenzoylethylene (5), 2,5-diphenylfurane (8),2-bromo-1,4-diphenylbutane-1,4-dione (4), cis- and trans- dibenzoyl-1,2-dibromo-ethane (6, 7) were obtained in a one pot reaction of 3 with Br-2. The reaction of ... -
Cyclohexenones Through Addition of Ethyl Acetoacetate to 3-Aryl-1-(thiophen-3-yl)prop-2-en-1-one Derivatives
Budak, Yakup; Findik, Esra; Ceylan, Mustafa (Bureau Scientific Publ, 2010)Chalcone derivatives 3a-i containing a thiophene ring were prepared by the condensation of 1-(thiophen-3-yl)ethanone with aromatic aldehydes in excellent yields. The Michael addition of ethyl acetoacetate 4 to chalcone ... -
Cyclohexenones Through Regioselective Addition of 1,3-Dicarbonyl Compounds to Terpenoid-Like Bischalcones
Findik, Esra; Budak, Yakup; Ceylan, Mustafa (Taylor & Francis Inc, 2009)Terpenoid-like bischalcones (3 and 4) were synthesized from the reaction of - and -ionones and benzaldehydes in excellent yields. The Michael addition of 1,3-dicarbonyl compounds to bischalcones (3 and 4) resulted in the ... -
Determination of the inhibition profiles of pyrazolyl-thiazole derivatives against aldose reductase and alpha-glycosidase and molecular docking studies
Demir, Yeliz; Taslimi, Parham; Kocyigit, Umit M.; Akkus, Musa; Ozaslan, Muhammet Serhat; Duran, Hatice Esra; Budak, Yakup (Wiley-V C H Verlag Gmbh, 2020)Aldose reductase (AR) is the first and rate-limiting enzyme of the polyol pathway, which converts glucose to sorbitol in an NADPH-dependent reaction. alpha-Glycosidase breaks down starch and disaccharides to glucose. Hence, ... -
Efficient synthesis and characterization of novel isoxazole derivatives including dihdyropyrazole and methanoisoindole moieties
Gurdere, Meliha Burcu; Erturk, Fatih; Budak, Yakup; Ceylan, Mustafa (Acg Publications, 2020)Isoxazole and pyrazole derivatives have a wide range of biological activity and they are of great interest to medicinal chemist. In this study, the synthesis and characterization of a series of novel hybrid molecules ... -
Investigation of Cytotoxic Effects of Inula Viscosa Extract
Inula viscosa is a type of Asteraceae family, which widely used for medicinal plant to treatment of different diseases. Inula viscosa contains many biological compounds, such as monoterpenes, sesquiterpenes, diterpenes, ... -
IODINE-CATALYZED ADDITION OF METHYL THIOGLYCOLATE TO CHALCONES
Gurdere, M. Burcu; Gezegen, Hayreddin; Budak, Yakup; Ceylan, Mustafa (Taylor & Francis Ltd, 2012)A series of novel beta-mercapto carbonyl compounds (3a-z), methyl 2-(3-oxo-1,3-diarylpropylthio)acetate, were synthesized and characterized via iodine-catalyzed addition of methyl thioglycolate to chalcones (1a-z). -
Potassium carbonate mediated one-pot synthesis and antimicrobial activities of 2-alkoxy-4-(aryl)-5H-indeno[1,2b] pyridine-3-carbonitriles
Ozturk, Sahin; Gurdere, Meliha Burcu; Gezegen, Hayreddin; Ceylan, Mustafa; Budak, Yakup (Acg Publications, 2016)2-Alkoxy-4-(aryl)-5H-indeno[ 1,2-b] pyridine-3-carbonitriles (3a-e and 4a-e) were synthesized via multicomponent reaction from 2-aryl-methylidineindan-1-ones (1a-e), malononitrile and K2CO3 in ethanol and/or methanol. The ... -
Potassium tert-Butoxide Catalyzed Synthesis and Characterization of Novel 3-Aryl-3-(phenylthio)-1-(thiophen-3-yl)propan-1-one Derivatives
Budak, Yakup (Wiley-V C H Verlag Gmbh, 2012)A series of thiophenyl-containing 3-thiophene derivatives (4a4i) were prepared via the reaction of chalcone-analogua compounds (3a3i) and thiophenol in the presence of catalytic amount of KOBu-t in CH2Cl2 with moderate to ... -
Potassium-Tertiary Butoxide-Assisted Addition of Thioglicolic Acid to Chalcone Derivatives Under Solvent-Free Conditions
Ceylan, Mustafa; Gurdere, Meliha Burcu; Gezegen, Hayreddin; Budak, Yakup (Taylor & Francis Inc, 2010)A series of chalcone derivatives containing thioglicolic acid (4a-j) was prepared by addition of thioglicolic acid to the chalcones (3a-j) in the presence of KOt-Bu under solvent-free conditions. The mechanistic pathway ... -
PREPARATION OF DIETHYL MALONATE ADDUCTS FROM CHALCONE ANALOGS CONTAINING A THIENYL RING
Budak, Yakup; Gurdere, M. Burcu; Kececi, Meryem; Ceylan, Mustafa (Chem Soc Ethiopia, 2010)Nine chalcone-diethyl malonate derivatives (4a-i) were prepared by the reaction of chalcone derivatives (3a-i) with diethyl malonate in the presence of a catalytic amount of KOt-Bu in CH(2)Cl(2) in good to excellent yields. ... -
Purification of glutathione S-transferase enzyme from quail liver tissue and inhibition effects of (3aR,4S,7R,7aS)-2-(4-((E)-3-(aryl)acryloyl)phenyl)-3a,4,7,7a-tetrahydro-1H-4,7-methanoisoindole-1,3(2H)-dione derivatives on the enzyme activity
Temel, Yusuf; Kocyigit, Umit M.; Taysi, M. Serif; Gokalp, Faik; Gurdere, Meliha Burcu; Budak, Yakup; Ceylan, Mustafa (Wiley, 2018)The use of quail meat and eggs has made this animal important in recent years, with its low cost and high yields. Glutathione S-transferases (GST, E.C.2.5.1.18) are an important enzyme family, which play a critical role ... -
Reaction of 2-phenyl- and 2-methyl-cycloalkanones with PBr(5) and influence of substituent on the addition of bromine atom
Ceylan, Mustafa; Guerdere, Meliha Burcu; Budak, Yakup (Asian Journal Of Chemistry, 2008)The reactions of 2-phenylketones 1, 4 and 12 with PBr(5) gave the alpha-brominated ketones as a regioselectivly and the alpha,alpha'-dibrominated ketones. But, the reactions of 2-methylketones 7a-c with PBr(5) gave only ...
