Browsing by Author "Ates, Omer"
Now showing items 1-20 of 53
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+45T > G single nucleotide polymorphism of adiponectin gene: Is it a factor in childhood obesity?
Kasap, Tuba; Ates, Omer; Ozer, Samet; Gul, Ali; Yilmaz, Resul; Sonmezgoz, Ergun; Demir, Osman (Derman Medical Publ, 2018)Aim: Childhood obesity is increasing in incidence and is strongly associated with obesity in adulthood. Several studies to explain the role of genetics in the pathogenesis of obesity have been performed. The aim of this ... -
Analyses of functional IL10 and TNF-alpha genotypes in Behcet's syndrome
Ates, Omer; Dalyan, Levent; Hatemi, Gulen; Hamuryudan, Vedat; Topal-Sarikaya, Aysegul (Springer, 2010)We aim to ascertain the possible involvement of functional IL10 and TNF-alpha promoter polymorphisms on the susceptibility to Behcet's syndrome (BS), to examine whether IL10 and TNF-alpha genotypes might work synergistically ... -
Analysis of CRABP2 and FABP5 genes in primary and recurrent pterygium tissues
Celik, Sumeyya Deniz; Ates, Omer (Springer, 2020)The etiology of pterygium remains unclear, but ultraviolet (UV) radiation is generally considered to be major risk factor. Pterygium has similarity features with many cancers, including inflammation, invasion, cell ... -
Analysis of dopamine beta hydroxylase gene polymorphisms in migraine
Sezer, Saime; Kurt, Semiha; Ates, Omer (Elsevier, 2016)Background: Migraine is a complex neurological disorder characterized by severe recurrent headache, nausea, vomiting, photophobia, and phonophobia. The frequency and duration of these symptoms varies among individuals. ... -
Analysis of estrogen and progesterone receptor gene polymorphisms in leiomyoma
Toprak, Muhammed; Ates, Omer; Ozsoy, Asker Zeki; Bozkurt, Nihan; Sondas, Saime Sezer; Cakmak, Bulent; Dogru, Hatice Yilmaz (Wiley, 2019)Background Leiomyoma, one of the most common benign tumors, causes morbidity during the reproductive years in women. The molecular pathogenesis of the disease is not clear. Leiomyomas are hormone-sensitive tumors affecting ... -
Analysis of manganese superoxide dismutase (MnSOD Ala-9Val) and glutathione peroxidase (GPx1 Pro 198 Leu) gene polymorphisms in psoriasis
Kalkan, Goknur; Seckin, Havva Yildiz; Bas, Yalcin; Benli, Ismail; Ozyurt, Huseyin; Ates, Omer; Ozdemir, Atiye (Springer, 2014)Recent studies have suggested the involvement of increased reactive oxygen species levels and decreased antioxidant system functions in psoriasis pathogenesis. In this study, we aimed to examine to investigate possible ... -
Analysis of manganese superoxide dismutase (MnSOD: Ala-9Val) and glutathione peroxidase (GSH-Px: Pro 197 Leu) gene polymorphisms in mood disorders
Cumurcu, Birgul Elbozan; Ozyurt, Huseyin; Ates, Omer; Gul, Isil Gogcegoz; Demir, Suleyman; Karlidag, Rifat (Assoc Basic Medical Sci Federation Bosnia & Herzegovina Sarajevo, 2013)We investigated the etiopathogenetic role of manganese superoxide dismutase (MnSOD) (Ala-9Val) and glutathione peroxidase (GSH-Px) (Pro 197 Leu) gene polymorphisms in patients diagnosed with major depressive disorder (MDD) ... -
Analysis of MMP2-1306C/T and TIMP2G-418C polymorphisms with relapsing remitting multiple sclerosis
Aksoy, Durdane; Ates, Omer; Kurt, Semiha; Cevik, Betul; Sumbul, Orhan (Bmj Publishing Group, 2016)Aims Multiple sclerosis (MS) is an autoimmune, inflammatory disease characterized by loss of myelin forming oligodendrocytes and changes in the blood-brain barrier. Matrix metalloproteinase (MMP) -2 and -9 are known to ... -
Analysis of Vitamin D Receptor (VDR) Gene Polymorphisms in Alopecia Areata
Ates, Omer (Derman Medical Publ, 2017)Aim: Alopecia areata (AA) is a disease characterized with hair loss on the hair skin any region of the body. This disease affects approximately 1-2% of the general population. The etiopathogenesis of this disease is unclear ... -
Analysis of WWOX gene expression and protein levels in pterygium
Bozkurt, Nihan; Ates, Omer (Springer, 2020)Purpose Pterygium, a degenerative and hyperplastic lesion, has premalignant properties as a tumor analog. WWOX is a tumor suppressor gene and involved in many signal pathways, such as cell proliferation, embryonic development, ... -
Association between 1603C > T polymorphism of DBH gene and bipolar disorder in a Turkish population
Ates, Omer; Celikel, Feryal Cam; Taycan, Serap Erdogan; Sezer, Saime; Karakus, Nevin (Elsevier Science Bv, 2013)Objectives: Dopamine-beta-hydroxylase (DBH) is the enzyme responsible for the conversion of dopamine (DA) to norepinephrine (NE, noradrenaline) which is a key neurotransmitter in the central and peripheral nervous systems. ... -
Association between C-Reactive Protein, Endothelial Nitric Oxide Synthase, and Interleukin-6 Gene Polymorphisms in Adolescents with a Family History of Premature Atherosclerosis
Celik, Atac; Ozcetin, Mustafa; Ates, Omer; Altunkas, Fatih; Karaman, Kayihan; Akar, Ilker; Ince, Ilker (Elsevier Science Inc, 2013) -
Association between fibromyalgia syndrome and polymorphism of the IL-4 gene in a Turkish population
Yigit, Serbulent; Inanir, Ahmet; Tekcan, Akin; Inanir, Sema; Tural, Sengul; Ates, Omer (Elsevier Science Bv, 2013)Purpose: Fibromyalgia (FM) syndrome is a form of non-articular rheumatism characterized by long term and widespread musculoskeletal pain, morning stiffness, sleep disturbance, paresthesia, and pressure hyperalgesia at ... -
The association between Interleukin (IL)-4 gene intron 3 VNTR polymorphism and alopecia areata (AA) in Turkish population
Kalkan, Goknur; Karakus, Nevin; Bas, Yalcin; Takci, Zennure; Ozuguz, Pinar; Ates, Omer; Yigit, Serbulent (Elsevier, 2013)Objective: Alopecia areata (AA) is hypothesized to be an organ-specific autoimmune disease of hair follicles mediated by T cells. As immunological and genetic factors have been implicated in the pathogenesis of AA, the ... -
Association Between Trp64arg Polymorphism of the beta 3 adrenoreceptor Gene and Female Sex in Obese Turkish Children and Adolescents
Yilmaz, Resul; Ates, Omer; Gul, Ali; Kasap, Tuba; Ozer, Samet; Ensari, Emel (Korean Soc Pediatric Gastroenterology & Nutrition, 2019)Purpose: The beta 3-adrenergic receptor (ADRB3) is expressed in visceral adipose tissue and has been speculated to contribute to lipolysis, energy metabolism, and regulation of the metabolic rate. In this study, we aimed ... -
Association of angiotensin converting enzyme (ACE) gene I/D polymorphism and rheumatoid arthritis
Yigit, Serbulent; Inanir, Ahmet; Tural, Sengul; Ates, Omer (Elsevier, 2012)We sought to determine the frequency of I/D polymorphism genotypes of angiotensin converting enzyme gene in Turkish patients with rheumatoid arthritis. Genomic DNA obtained from 256 individuals (110 patients with rheumatoid ... -
Association of IL-4 gene VNTR variant with deep venous thrombosis in Behcet's disease and its effect on ocular involvement
Inanir, Ahmet; Tural, Sengul; Yigit, Serbulent; Kalkan, Goknur; Pancar, Gunseli Sefika; Demir, Helin Deniz; Ates, Omer (Molecular Vision, 2013)Purpose: Behcet's disease (BD) is a systemic vasculitis characterized by inflammatory lesions of the urogenital mucosa, eyes, skin, central nervous system, and joints. Vein thrombosis constitutes the most frequent vascular ... -
Association of interleukin (IL)-4 gene intron 3 VNTR polymorphism with multiple sclerosis in Turkish population
Karakus, Nevin; Yigit, Serbulent; Kurt, Gulsum Semiha; Cevik, Betul; Demir, Osman; Ates, Omer (Elsevier Science Inc, 2013)Objective: Genetic risk factors are known to contribute to the etiology of multiple sclerosis (MS). Interleukin (IL)-4 gene polymorphisms have been associated with immune-mediated diseases. The aim of this study was to ... -
Association of Macrophage Migration Inhibitory Factor Gene -173 G/C Polymorphism (rs755622) with Familial Mediterranean Fever in Children
Objectives The aim of this study was to identify the genotypic analysis and allele frequencies of the -173 G/C polymorphism in the macrophage migration inhibitory factor (MIF) gene in children diagnosed with familial ...